Protandim Tri-Synergizer is designed to help support healthy aging, daily health, mental clarity, and a balanced mood by activating production of key compounds that neutralize, energize, and revitalize cellular function.*

You can’t stop time, but as the years pass, living life with the same energy, focus, and clarity can become a little harder. Aging can be wonderful. It comes wisdom, maturity, a career, and often a family. But it can also come with feeling tired, a little slower, and less vibrant.   

But you deserve to feel your best every day, no matter your age or stage of life. The secret to maintaining a healthier body and mind is found inside your cells. By supporting the health of your cells and targeting the root causes of aging, you can restore youthful function to the trillions of cells inside your body.*

That’s why we created patent-pending Protandim Tri-Synergizer—a supplement trio proven to provide maximum activation of 3 key genetic functions that may have slowed with age. In an in-house survey, people who use Tri-Synergizer reported benefits for a healthy body, mind, and mood:

  • More energy and vitality*
  • Mental clarity and focus*
  • Improved sleep*
  • Better resilience to stress*
  • Boost in mood in motivation*

You can activate ageless vitality today. Revive and thrive with Protandim Tri-Synergizer.*

To understand what makes Tri-Synergizer so effective, let’s take a look at the 3 reasons we age, and how it addresses each.

Three reasons you age

To function at a high level, your body relies on a complex network of signals between cells and genes. Your genes tell your cells to make proteins responsible for carrying out various functions in your body. Those messages are carried along pathways and received by receptors inside your cells. When working at its best, this process keeps you feeling vibrant and youthful—with energy, clarity, and overall wellbeing.

But after age 35, cells and genes can gradually lose their ability to function as well as they did in earlier years. This is likely due to 3 causes:

  1. Oxidative stress. The simple act of living creates free radicals. The effects of free radicals and other oxidants can accumulate over time and wear cells down. This is known as oxidative stress. Left unchecked, it can inhibit cells’ ability to communicate and function. That’s why antioxidants––with their ability to counteract this process––are so important.

    Learn more about the oxidative stress theory of aging.
  2. Mitochondrial decline. Mitochondria turn the food you eat into the energy you need to power your whole body—from your heart to your brain. They’re essential for health. In fact, mitochondria produce about 95% of the energy you need to function every second of every day. However, as the years pass, mitochondria may become less effective as they break down and die off. This can impact everything from feeling sluggish to not sleeping as well.

    Learn more about the mitochondrial theory of aging.
  3. Sirtuin activation. Sirtuins are a little-known but powerful family of proteins that activate during caloric restriction, and they play an essential role in your body’s fight aging. When active, these proteins protect the longevity of cells and support cardiovascular, metabolic, and cognitive health by clearing out cellular waste. Further research has revealed a molecule that declines with age called NAD+ triggers sirtuin activation. Some foods can help increase NAD.

    Learn more about the sirtuin theory of aging.

How does Protandim Tri-Synergizer address all 3 causes of aging?

Tri-Synergizer consists of 3 products that work together to help you revive and thrive in 3 important ways:

  1. Protandim Nrf2 Synergizer neutralizes the effects of oxidative stress by activating your body’s ability to produce its own powerful antioxidants to fight against cellular damage.*
  2. Protandim NRF1 Synergizer energizes your cells by helping the body make more mitochondria and supplies the nutrients they need to ramp up cellular energy for whole-body health.*
  3. Protandim NAD Synergizer revitalizes peak cellular efficiency by doubling the production of NAD+—a key enzyme that tells your body to clear out cellular waste. It also double sirtuin activity in 24 hours.*

But that’s just part of the story.

Better together: the synergistic impact of Protandim Tri-Synergizer

While all 3 Protandim products come with powerful benefits, an in-house study showed that when they’re taken together, those benefits compound significantly.

When it came to the effect Tri-Synergizer had on Nrf2 genes, there was a 78% increase in the gene responsible for fighting oxidative stress.*

Nrf2 Synergizer Study Graph 1


The study also revealed a 90% increase in the Nrf1 gene responsible for overall cellular and mitochondrial health, and a 120% increase in the gene responsible for mitochondrial turnover and biogenesis.*

And when taken together, there was a 128% increase in a key enzyme in the NAD pathway along with a 227% increase in the central enzyme for NAD synthesis.*

For a more in-depth exploration of how Tri-Synergizer is changing the conversation on healthy aging, check out Protandim Tri-Synergizer Questions Answered.

Three products. One powerful solution.

From more energy and improved cognitive ability to better sleep and feeling great throughout the day, maintaining the vibrancy starts with better cellular health. And that’s exactly why we created Protandim Tri-Synergizer. It’s more than 3 great products. Tri-Synergizer is scientifically formulated to work better together. And with its compound effects, you get maximum activation, so you can feel better and live better every single day.*

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.